The profens are a class of nonsteroidal anti-inflammatory drugs.[1] Profens are also known as 2-arylpropionic acids to reflect their chemical structure.[2] The most common example of a profen is ibuprofen, which has been sold under the brand name Profen among others.
Left: general chemical structure of profens (Ar = aryl group). Right: chemical structure of ibuprofen
Other drugs in the class include:
References
edit- ^ Evans, A. M. (1996). "Pharmacodynamics and pharmacokinetics of the profens: Enantioselectivity, clinical implications, and special reference to S(+)-ibuprofen". Journal of Clinical Pharmacology. 36 (12 Suppl): 7S–15S. doi:10.1002/j.1552-4604.1996.tb00003.x. PMID 9013378. S2CID 26944804.
- ^ Landoni, M.; Soraci, A. (2001). "Pharmacology of Chiral Compounds 2-Arylpropionic Acid Derivatives". Current Drug Metabolism. 2: 37–51. doi:10.2174/1389200013338810. PMID 11465150.
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