Bendazac

Bendazac (or bendazolic acid) is a nonsteroidal anti-inflammatory drug (NSAID) used for joint and muscular pain.

Bendazac

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Topical
ATC code	M02AA11 (WHO) S01BC07 (WHO)
Identifiers
IUPAC name [(1-benzyl-1H-indazol-3-yl)oxy]acetic acid
CAS Number	20187-55-7 Y
PubChem CID	2313
ChemSpider	2223 Y
UNII	G4AG71204O
KEGG	D01594 Y
ChEBI	CHEBI:31257 N
ChEMBL	ChEMBL1089221 Y
CompTox Dashboard (EPA)	DTXSID1048334
ECHA InfoCard	100.039.594
Chemical and physical data
Formula	C16H14N2O3
Molar mass	282.299 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(O)COc2nn(c1ccccc12)Cc3ccccc3
InChI InChI=1S/C16H14N2O3/c19-15(20)11-21-16-13-8-4-5-9-14(13)18(17-16)10-12-6-2-1-3-7-12/h1-9H,10-11H2,(H,19,20) Y Key:BYFMCKSPFYVMOU-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Synthesis

Principal action is inhibition of protein denaturation.

Bendazac synthesis: BE 699226 ; G. Palazzo, U.S. patent 3,470,194 (1967, 1969 both to Francesco Angelini).

Use of chloroacetamide in the alkylation step, followed by acid hydrolysis produces bendazac (instead of benzydamine).

See also

• Benzydamine