Benigno Aquino may refer to:
- Benigno Aquino Sr. (1894–1947), Filipino politician and speaker of the House of Representatives from 1943 to 1944
- Benigno Aquino Jr. (1932–1983), Filipino politician, son of Benigno Sr., former senator, and former governor of Tarlac
- Benigno Aquino III (1960–2021), Filipino politician, son of Benigno Jr., and 15th president of the Philippines
- Paolo Benigno Aquino IV (born 1977), Filipino politician, nephew of Benigno Jr.