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Summary
DescriptionPicture2 englisch.jpg
Germinal centres of SLE patients and controls (schematic). Red: CD68 in tingible body macrophages; black: TUNEL positive apoptotic cells.
Healthy donors with florid germinal centres show giant tingible body macrophages (TBM) containing ingested apoptotic cells and no uningested apoptotic cells outside the TBM.
Patients with follicular lymphoma show small tingible body macrophages (TBM) containing few ingested apoptotic cells however, there are no uningested apoptotic cells outside the TBM.
Some patients with SLE (1) show lack of TBM and many uningested apoptotic cells decorating the surfaces of spindle-shaped cell, presumably follicular dendritic cells (SLE 1).
Some few patients with SLE show TBM containing few ingested apoptotic cells and many uningested apoptotic cells outside the TBM (SLE 2). However, about 50 % of the SLE patients show are rather normal germinal centre.
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{{Information |Description= germinal centres and controls |Source= own work |Date= 10.10.07 |Author= Dana Weidner |Permission= {{GFDL-self}} |other_versions= }}