Gap junction beta-7 protein (GJB7), also known as connexin-25 (Cx25), is a protein that in humans is encoded by the GJB7 gene.[3]
| GJB7 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | GJB7, CX25, bA136M9.1, connexin25, gap junction protein beta 7 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 611921; HomoloGene: 89311; GeneCards: GJB7; OMA:GJB7 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Function
editConnexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[3][4]
References
edit- ^ a b c GRCh38: Ensembl release 89: ENSG00000164411 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b "Entrez Gene: gap junction protein".
- ^ Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038. S2CID 225894.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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