β-Zearalenol is a nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp.[1] It is the β epimer of α-zearalenol and along with α-zearalenol is a major metabolite of zearalenone formed mainly in the liver but also to a lesser extent in the intestines during first-pass metabolism.[2][3] A relatively high proportion of α-zearalenol is formed from zearalenone compared to β-zearalenol in humans.[3] β-Zearalenol is about the same or slightly less potent as an estrogen relative to zearalenone.[1]
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| Other names | beta-Zearalenol; beta-trans-Zearalenol |
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| ECHA InfoCard | 100.190.517 |
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| Formula | C18H24O5 |
| Molar mass | 320.385 g·mol−1 |
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See also
edit- Taleranol (β-zearalanol)
- Zeranol (α-zearalanol)
- Zearalanone
References
edit- ^ a b Bottalico A, Logrieco A, Visconti A (January 1989). "Fusarium species and their mycotoxins in infected cereals in the field and in stored grains". In Chelkowski J (ed.). Fusarium: Mycotoxins, Taxonomy, Pathogenicity. Elsevier Science. pp. 85–119. ISBN 978-1-4832-9785-9.
- ^ Alldrick AJ, Hajšelová M (January 2004). "Zearalenone". In Magan N, Olsen M (eds.). Mycotoxins in Food: Detection and Control. Woodhead Publishing. pp. 353–366. ISBN 978-1-85573-733-4.
- ^ a b Eriksen GS, Alexander J (1998). "Zearalenone". Fusarium Toxins in Cereals: A Risk Assessment. Nordic Council of Ministers. pp. 61–. ISBN 978-92-893-0149-7.