Dr Kristina Micheva is a Bulgarian-American neuroscientist[1] at Stanford University.[2] She is one of the inventors of Array Tomography, a technique in which proteins are detected with antibodies in ultra-thin sections of brain tissue using confocal microscopy.[3][4][5]
Kristina Micheva | |
|---|---|
 Micheva in 2021 | |
| Born | Sofia, Bulgaria |
| Known for | Invention of Array Tomography |
| Academic background | |
| Education | Sofia University University of Montreal |
| Academic work | |
| Discipline | Neuroscience |
| Institutions | Stanford University |
Education
editMicheva was a biology major at the University of Sofia. She received a masters in plant ecology at the University of Sofia as well.[1] After graduation, she worked in a lab at a medical university in Sofia where she learned electron microscopy and how to work with brain sections.[6] She moved to Montreal, Quebec to pursue a PhD in neuroscience (receiving the degree in 1996).[6] In 1996 she participated in the Marine Biological Laboratory Neurobiology Course,[7] in which she later taught as faculty (2006-2014).[8]
Research
editMicheva's main interest is in studying how brain structures develop and change with experience.[9] During her PhD, she studied how sensory experience affects cortical development.[9]
Invention of Array Tomography
editMicheva co-developed the Array Tomography technique with Stephen J Smith. In this technique, proteins are detected with antibodies in ultra-thin sections of brain tissue using confocal microscopy.[10][5][3] This technique can be combined with electron microscopy and is the only technique that allows a voxel-conjugate joining of fluorescence and electron microscopy methods.[11] Given the advantages of this method, it is considered an excellent choice for challenging explorations of cellular architectures in mature and developing tissues.[11]
Personal life
editIn her free time, Micheva practices karate. She is a third-degree black belt as of the spring of 2021, and teaches a children's karate class.[12]
References
edit- ^ a b "Episode 02: Kristina Micheva, PhD". Conjugate: Illustration and Science Blog. Retrieved 2021-04-26.
- ^ "Kristina Micheva's Profile | Stanford Profiles". profiles.stanford.edu. Retrieved 2021-05-03.
- ^ a b "What is Immunofluorescent Array Tomography?". News-Medical.net. 2019-12-10. Retrieved 2021-05-02.
- ^ "Synapses on Stage". The Scientist Magazine®. Retrieved 2021-04-28.
- ^ a b Pastrana, Erika (January 2011). "Unraveling synapse diversity". Nature Methods. 8 (1): 16. doi:10.1038/nmeth0111-16. ISSN 1548-7105. S2CID 29464084.
- ^ a b "Episode 02: Kristina Micheva, PhD". Conjugate: Illustration and Science Blog. Retrieved 2021-04-27.
- ^ "Neurobiology 1996 (Course) | History of the Marine Biological Laboratory". amphora.asu.edu. Retrieved 2021-05-03.
- ^ "Kristina Micheva (Person) | History of the Marine Biological Laboratory". amphora.asu.edu. Retrieved 2021-05-03.
- ^ a b "Episode 02: Kristina Micheva, PhD". Conjugate: Illustration and Science Blog. Retrieved 2021-05-02.
- ^ "Touring Memory Lane Inside The Brain". NPR.org. Retrieved 2021-04-28.
- ^ a b Smith, Stephen J. (2018-09-06). "Q&A: Array tomography". BMC Biology. 16 (1): 98. doi:10.1186/s12915-018-0560-1. ISSN 1741-7007. PMC 6127925. PMID 30189863.
- ^ "Episode 02: Kristina Micheva, PhD". Conjugate: Illustration and Science Blog. Retrieved 2021-04-28.