Makio may refer to:

People with given name

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  • Makio Akiyama (秋山 万喜夫, born 1950), Japanese astronomer
  • Makio Inoue (井上 真樹夫, 1938–2019), Japanese voice actor
  • Makio Madarame (班目 真紀夫, born 1972), Japanese former cyclist

People with surname

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  • Haruki Makio (牧尾 晴喜, born 1974), Japanese architectural translator