A monoamine receptor is a receptor for the monoamine neurotransmitters and/or trace amines, endogenous small-molecule signaling molecules with a monoamine structure. The monoamine receptors are almost all G protein-coupled receptors, with the serotonin 5-HT3 receptor being a notable exception as a ligand-gated ion channel.[1] Monoamine receptors are the biological targets of many drugs; such drugs may be referred to as "monoaminergic".
List of receptors
editMonoamine receptors include the following classes:
- Adrenergic receptors – bound by epinephrine (adrenaline) and norepinephrine (noradrenaline)
- Dopamine receptors – bound by dopamine
- Histamine receptors – bound by histamine
- Melatonin receptors – bound by melatonin
- Serotonin receptors – bound by serotonin (5-HT)
- Trace amine-associated receptors – bound by trace amines, thyronamines, monoamine neurotransmitters (TAAR1 only), and trimethylamine (TAAR5 only)
References
edit- ^ a b Martin, Andres; Scahill, Lawrence; Kratochvil, Christopher (14 December 2010). Pediatric Psychopharmacology. Oxford University Press. p. 31. ISBN 9780199842667. Retrieved 27 January 2017.
The 5-HT3 receptor is the only monoamine receptor coupled to an ion channel, probably a Ca2+ channel.
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