Rio Medina or Riomedina is an unincorporated community in Medina County, Texas, United States.[1] It is located approximately six miles north of Castroville[1] and is part of the San Antonio Metropolitan Statistical Area. According to the 2006–07 Texas Almanac, it had a population of 60 people in 2000. According to an online community profile, Rio Medina has a population of 541 people (population year not provided).[2]

The town is located on the Medina River and is approximately 7.5 miles south of Medina Lake.[1] Rio Medina supported construction workers during the Medina Lake Dam in the early 1910s.

Rio Medina has a post office located on highway FM 471 inside the general store.

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29°26′23″N 98°53′03″W / 29.43968°N 98.88419°W / 29.43968; -98.88419