Talk:Neutropenic enterocolitis
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Most doctors call this typhlitis or neutropenic enterocolitis, not caecitis.
editMost doctors call this neutropenic enterocolitis or typhlitis, not caecitis.
Typhlitis is the commonly accepted and used term
editTyphlitis derives from the greek "typhlon," (Latin cecum).
In PubMed,
Typhlitis gets 302 hits.
An attempt to search for caecitis is redirected by PubMed to a search for typhlitis:
PubMed's Search Details for the "caecitis" search are: "typhlitis"[MeSH Terms] OR "typhlitis"[All Fields] OR "caecitis"[All Fields]
Note it is "typhlitis" that is the MeSH Term
Google hits Feb 4 2010:
148,000 Typhlitis
23,500 "neutropenic enterocolitis"
22,300 Caecitis
2,040 Typhlenteritis
this article should be renamed Typhlitis
editThat's what doctors and everyone else calls it, by a rather large margin.
66.167.95.147 (talk) 22:38, 14 March 2010 (UTC)
.
Working rewrite for "cause" section, noting C. Difficile overgrowth from incautious antibiotic use.
editCause
editThe condition is usually caused by gram positive enteric commensal bacteria of the gut (gut flora).
Typhlitis affects immunocompromised patients, such as those undergoing chemotherapy,[1] patients with AIDS, kidney transplant patients, or the elderly[2]. Clostridium difficile is a species of Gram-positive bacteria that causes diarrhea and other intestinal disease when competing bacteria are wiped out by antibiotics or chemotherapy.
References
- ^ Keidan, RD (1989). "Recurrent typhlitis. A disease resulting from aggressive chemotherapy". Dis Colon Rectum. 32(3): 206–9. PMID 2920627.
{{cite journal}}:|access-date=requires|url=(help); Unknown parameter|coauthors=ignored (|author=suggested) (help); Unknown parameter|month=ignored (help) - ^ Stoehr TM and Koslin DB. 2004. Typhlitis. emedicine.com.
Treatment draft
editTyphlitis is a medical emergency. It has a very poor prognosis and is often fatal unless promptly recognized and aggressively treated.[1] Successful treatment hinges on:
- ... 1) early diagnosis provided by a high index of suspicion and the use of CT scanning, 2) nonoperative treatment for uncomplicated cases, and 3) elective right hemicolectomy to prevent recurrence....
- ... The authors have found nonoperative treatment highly effective in patients who do not manifest signs of peritonitis, perforation, gastrointestinal hemorrhage, or clinical deterioration. Recurrent typhlitis was frequent after conservative therapy (recurrence rate, 67 percent), however. [2] ...
--Ocdnctx (talk) 18:55, 26 August 2012 (UTC)
References
- ^ Keidan, RD (1989). "Recurrent typhlitis. A disease resulting from aggressive chemotherapy". Dis Colon Rectum. 32(3): 206–9. PMID 2920627.
{{cite journal}}:|access-date=requires|url=(help); Unknown parameter|coauthors=ignored (|author=suggested) (help); Unknown parameter|month=ignored (help) - ^ Keidan, RD (1989). "Recurrent typhlitis. A disease resulting from aggressive chemotherapy". Dis Colon Rectum. 32(3): 206–9. PMID 2920627.
{{cite journal}}:|access-date=requires|url=(help); Unknown parameter|coauthors=ignored (|author=suggested) (help); Unknown parameter|month=ignored (help)
does anyone have access to this review or the review it references (circa 2005)?
editThe review may provide valuable information:
- This review will cover the recent literature pertaining to the pathogenesis, diagnosis, and management
Davila ML.
Neutropenic enterocolitis.
Curr Opin Gastroenterol. 2006 Jan;22(1):44-7.
Abstract
PURPOSE OF REVIEW:
This review will cover the recent literature pertaining to the pathogenesis, diagnosis, and management of patients with neutropenic enterocolitis.
RECENT FINDINGS:
Neutropenic enterocolitis, also referred to as typhlitis, is a life-threatening gastrointestinal complication of chemotherapy, most often associated with leukemia or lymphoma. Recently, a larger number of reports have been published of individuals presenting with this syndrome after being treated with newer chemotherapeutic agents for solid tumors such as non-small cell lung, ovarian, and peritoneal cancer, as well as following autologous stem cell transplantation. Recent studies have also better characterized computed tomographic and ultrasonographic features of this entity that can help differentiate neutropenic enterocolitis from other gastrointestinal complications. A newly published systematic analysis of the literature, which included 145 articles, defines appropriate diagnostic criteria and treatment recommendations.
SUMMARY:
Neutropenic enterocolitis is a serious, potentially lethal complication of anticancer therapy. The studies discussed in this review will help the practitioner make an appropriate, early diagnosis and implement a therapeutic program that would improve the outcome of these patients.